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TIL Therapies: A New Paradigm in Cancer Treatment

Till date, several clinical trials have demonstrated the efficacy and therapeutic superiority (over conventional treatment options) of TIL-based therapies.

Modified tumor-infiltrating lymphocytes or TIL therapies have emerged as a viable and potent option to selectively eradicate the tumor population, with minimal side effects. Their tumor-cell killing efficiency is attributed to the fact that they are pre-sensitized to cancer specific antigens.

Ongoing and planned clinical research initiatives in this direction are driven by encouraging results achieved in past trials, which were mostly focused on various hematological cancers and solid tumors. Driven by the ongoing pace of innovation in this field, sufficient financial support from investors and encouraging clinical trial results, the TIL-based therapy market is likely to witness significant growth in the foreseen future.

Current Market Landscape of TIL-based Therapies
Over 75 TIL immunotherapies are being evaluated across different stages of preclinical / clinical development, either as monotherapies or in combination with other drugs. Both industry and non-industry players have demonstrated keen interest in the development of novel TIL-based cell therapies. Further, melanoma emerged as the most popular target indication in this domain. More than 95% of the therapy candidates that are being developed to target a wide range of disease indications are autologous in nature.
Driven by a promising development pipeline and encouraging clinical trial results, the TIL therapy market is likely to carve out a significant share of the multibillion-dollar cancer immunotherapy market.

Rising Interest in TIL-based Therapies
The growing interest in this field is therapies is reflected from the increase in the partnerships focused on R&D of such therapies. Several investors, having realized the opportunity within this upcoming segment of T-cell immunotherapy, have invested USD 2.7 billion, across 30 instances, since 2013. Further, in the last 10 years, close to 95 clinical trials evaluating TIL-based therapies have been registered across different geographies for the evaluation of TIL-based therapies. Mostly driven by the need for effective treatment options for cancer, the TIL-based therapy pipeline is expected to steadily grow over the coming years.

For additional details, please visit
https://www.rootsanalysis.com/blog/til-based-therapies/ or email sales@rootsanalysis.com

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About Roots Analysis
Roots Analysis is a global leader in the pharma / biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights.

Contact:
Ben Johnson
+1 (415) 800 3415
Ben.johnson@rootsanalysis.com

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Viral Clearance and Viral Testing Services

Considering the rising demand for biologics, innovators in the biopharmaceutical industry are constantly exploring avenues that would enable them to overcome the existing technical and operational challenges related to viral-clearance and testing for timely approval of biologics.

Outsourcing the viral clearance and viral testing studies has emerged as a promising alternative for most of the manufacturers. Despite being one of the crucial steps amongst all the steps involved in the production of biologics, this service is heavily outsourced in the biopharmaceutical industry. Currently, it is estimated that more than 70% of these services are employed by biopharmaceutical and pharmaceutical companies. Service providers across the globe offering this service are large players.

Of these, close to 80% players provide services for both, viral clearance and viral testing of different type of biologics. Of the players have established their facilities in Europe. Within this region, UK has the maximum number of facilities (over 21%), followed by Germany (more than 15%) and France (close to 10%). Patents have been filed / granted over last few years. Of these, over 40% patents are granted by organizations headquartered in the US whereas close to 25% patent applications are filed by organizations headquartered in China.

As projected by Roots Analysis, more than 55% of the share is captured by viral removal, in the viral clearance market. As projected by Roots Analysis, 40% of the share is captured by North America, in this market. Driven by the rising interest in research and development activities and the demand for the viral clearance and viral testing services, the future opportunities and growth associated with this market are anticipated to witness a noteworthy growth in the foreseen future. Specifically, in terms of end-users, the market is anticipated to be driven by biotechnology and pharmaceutical industry.

For additional details, please visit
https://www.rootsanalysis.com/blog/viral-clearance-and-viral-testing-services/ or email sales@rootsanalysis.com

You may also be interested in the following titles:
1. Smart Labels Market: Industry Trends and Global Forecasts, 2022-2035
2. 4D Bioprinting Market : Industry Trends and Global Forecasts, 2022-2035


About Roots Analysis
Roots Analysis is a global leader in the pharma / biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights.

Contact:
Ben Johnson
+1 (415) 800 3415
Ben.johnson@rootsanalysis.com

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